|
 |
Science > Knockout Mice
The following information is about Knockout Mice.
Knockout Mice Defined
Mice whose genome contains a gene whose function has been disrupted, or "knocked- out". A common method of producing disabled genes using recombinant DNA technology is by inserting an antibiotic resistance gene into the normal DNA sequence of a clone of the gene being studied. This disrupts the gene's action, thereby preventing it from making an active protein product. Cells in which this transfer is successful are then injected into mouse embryos, producing chimeric mice. These mice are bred to yield a strain in which all the cells contain the knocked- out gene. Knockout mice are used as animal models for various diseases, such as cystic fibrosis, and are helping to clarify the functions of the genes studied within the fields of immunology, cancer genetics, and developmental biology.
This definition is in context to Science. See more contextual defintions for Knockout Mice.
Are you looking for additional Science > Knockout Mice news? Try our new "Knockout Mice News Focus" area.
Off-site Knockout Mice Links, User Submitted
The following links have been collected through user bookmark submission in the Knockout Mice category. Please note, because these resources are off-site we cannot guarantee the accuracy or quality of any information.
Sat Feb 28
- Scientists Discover Why Teeth Form in a Single Row - URMC Press Room: A system of opposing genetic forces determines why mammals develop a single row of teeth, while sharks sport several, according to a study published today in the journal Science. When completely understood, the genetic program described in the study may help guide efforts to re-grow missing teeth and prevent cleft palate, one of the most common birth defects.
Sat Nov 1
- DeltaOne? | Overview: Knockout mouse database with over 900 KO and phenotypes.
Tue Oct 30
- Knockout Transgenic Mouse
- CMC Activity Center : Transgenic and Knockout Mice : Resources : Targeting for Beginners : CMC?Nature Gateway: RPCI-23 BAC library
Mon Oct 8
Wed Aug 22
Thu Mar 15
Thu Feb 8
Fri Jul 7
If you would like to find additional social bookmark based links on the topic of we recommend the Open Tag Directory > Knockout Mice. If you would like to find related tags we recommend Tag Patterns > Knockout Mice
Off-site Knockout Mice Research Links
If you still need additional information on Knockout Mice then we suggest the following off-site resources. Please note, because these resources are off-site we cannot guarantee the accuracy or quality of any information.
- A9 > Knockout Mice
- Alexa > Knockout Mice
- DMOZ > Knockout Mice
- Feeds Filtered > Knockout Mice
- Google > Knockout Mice
- News Meme > Knockout Mice
- Nuah: News > Knockout Mice
- The Feed Directory > Knockout Mice
- OBP > Knockout Mice
- Open Tag Directory > Knockout Mice
- Podzy > Knockout Mice
- Yahoo > Knockout Mice
Science Topics
Everything you need to know about Science
Science
If you know the Science Term Name use the links below to quickly jump to your desired focus.
Bookmark Us
The On Topic Network
This website is part of The On Topic Network.
Thank You
Science.On-Topic.net was developed by Odin Metatech, Inc and runs on the Odin Assemble platform.
License
This work is licensed under Creative Commons.