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Science > Allosteric Selection
The following information is about Allosteric Selection.
Allosteric Selection Defined
An in vitro selection method for aptamers that is performed entirely in solution by virtue of the unique design of the population. A random sequence domain is inserted into a tolerant region of a catalytic RNA or DNA and the molecules recovered from selection demonstrate ligand-dependent catalytic function. Such a selection eliminates the need to immobilize the ligand on a column, and will not be subject to interference due to column immobilization.
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